Pigmentation is one of those skin problems that never really “goes away” on its own. Every week at my clinic, I meet patients who tell me:
“Doctor, I’ve tried everything:- creams, facials, even expensive treatments but my pigmentation keeps coming back.”
I completely understand the frustration. Pigmentation, whether from sun damage, acne, pregnancy, or hormones, is more than just a cosmetic issue. It can make your skin look dull, patchy, and uneven, affecting confidence deeply.
That’s why I often turn to medical-grade depigmentation treatments. At Dr. Ujjwala Skin Clinic, Raipur, two of the most effective options I use are Cosmelan® and Dermamelan®, both developed by Mesoestetic®.
Let me walk you through both.
Cosmelan®: The Deep Peel Powerhouse
Treatment:-
When pigmentation is not too severe, my first choice is usually Cosmelan®. I like to call it a deep peel powerhouse.
It works by reducing the overproduction of melanin, which is the pigment that causes dark patches. At the same time, it refreshes the skin’s surface, leaving the face looking brighter, smoother, and more even-toned.
The treatment itself has two parts:
In-clinic mask application: I apply a peel mask at the clinic, and here’s the part patients always find surprising it stays on the skin for about 12 hours.
Home-care maintenance: After the mask is removed, patients continue with a specially prescribed home-care cream to maintain and enhance the results.
Effective For:-
I’ve seen Cosmelan work beautifully for:
▪️Melasma (often triggered by pregnancy or hormones)
▪️Sun damage and tanning
▪️Post-acne dark spots
▪️Dull, uneven skin tone
Many of my patients tell me they love how their skin doesn’t just look clearer, but also feels refreshed and radiant after Cosmelan®.
Dermamelan®: For Resistant Pigmentation
The Method
Now, when pigmentation is stubborn or keeps coming back, I recommend Dermamelan®. This is the stronger, medical-grade version of Cosmelan®.
It’s particularly effective for pigmentation caused by:
▪️Hormonal changes (like after pregnancy or from contraceptive pills)
▪️Post-acne pigmentation that refuses to fade
▪️Severe, resistant melasma
Treatment
The treatment has a more intensive in-clinic phase, followed by a strict four-month home-care plan. Because of its strength, patients may notice more redness, peeling, and sensitivity compared to Cosmelan®. But in my experience, this phase is temporary and well worth it, given the long-lasting results.
Benefits
Targets deep-rooted, resistant pigmentation
▪️Dual action: corrects current spots and prevents recurrence
▪️Stronger skin renewal, leaving a brighter, healthier look
▪️Results that can last up to a year or more with proper care
How to Choose Between the Two
I don’t believe in “one-size-fits-all” when it comes to skin. The choice depends on:
▪️Severity of pigmentation
▪️Whether it’s new or long-standing
▪️Patient history and lifestyle
For mild to moderate pigmentation, I choose Cosmelan.
For resistant, recurrent, or hormonal pigmentation, I prefer Dermamelan.
What Patients Can Expect
▪️First few days: Redness, peeling, tightness (completely normal).
▪️2–3 weeks (Cosmelan®): Pigmentation visibly lightens, skin looks brighter.
▪️3–4 weeks (Dermamelan®): More dramatic changes, with deeper, longer-lasting improvements.
Side Effects
Both are safe treatments, but temporary side effects include:
Redness
Mild peeling
Sensitivity
Warmth or tightness of the skin
Dermamelan® can sometimes feel a bit “stronger,” but with the right aftercare, patients adjust quickly.
Results
Cosmelan®: Softer, smoother skin and noticeable reduction in pigmentation within 2–3 weeks.
Dermamelan®: Clearer, even-toned skin in 3–4 weeks, with results that last much longer.
I’ve had patients with years of hormonal pigmentation who finally saw real improvement after Dermamelan®.
Aftercare
Questions Patients Ask
Q1. Which one is stronger?
Dermamelan® is stronger, best for resistant pigmentation.
Q2. Do I need to take leave from work?
No, but expect some redness and peeling in the first few days.
Q3. Will my pigmentation return?
With proper aftercare, Dermamelan® significantly reduces recurrence.
Q4. How long does the mask stay on?
Cosmelan®’s clinic mask stays on for about 12 hours before removal at home.
Q5. Is it safe for Indian skin?
Yes, both treatments are safe and effective for Indian skin tones.
Pigmentation is tricky, but it’s not untreatable. With the right approach, patients see real, lasting improvements.
For mild to moderate pigmentation, I usually recommend Cosmelan®—my deep peel powerhouse.
For resistant or hormonal pigmentation, Dermamelan® is my go-to choice.
At Dr. Ujjwala Skin Clinic, Raipur, Bhilai I always personalize treatment plans, because every skin tells a different story. If pigmentation has been affecting your confidence, let’s sit together and find the right solution for you.
👉 Book your consultation today, and let’s begin your journey to brighter, healthier skin
